Sequelae of congenital oropharyngeal teratoma in the oral cavity of the child

case report

Authors

  • Letícia Bruno Qualhato Federal University of Uberlândia
  • Ana Carolina Candelas Peixoto Federal University of Uberlândia
  • Késia Lara dos Santos Marques Federal University of Uberlândia
  • Celia Regina Moreira Lanza Federal University of Uberlândia
  • Luiz Roberto da Silva Federal University of Uberlândia
  • Guilherme Silva de Mendonça Hospital de Clínicas da Universidade Federal de Uberlândia https://orcid.org/0000-0001-5635-2708
  • Fabiana Sodré de Oliveira Federal University of Uberlândia

DOI:

https://doi.org/10.31686/ijier.vol9.iss7.3225

Keywords:

Teratoma, Oropharynx, Child, Preschool, Oral Cavity, Case Reports

Abstract

Congenital oropharyngeal teratoma is a rare tumor subtype with cells from the three germ layers, majorly being benign. Whereas teratoma develops early in intrauterine life, thus affecting the growth and development of adjacent structures, the purpose of this case report is to present the sequelae of this tumor in a child's oral cavity. Female child, 2 years and 3 months old referred by the otorhinolaryngologist for dental evaluation. The mother´s main complaint was the the child could not close her mouth. According to the child's medical record, at 34th week of gestation, during the routine ultrasound examination, the presence of the anechoic tumor mass was observed without Doppler signal, presenting a 3.2cm x 2.4cm diameter outside through the oral cavity. At 17 and 32 days of life, respectively, the excision of the largest and residual tumor located on the floor of the mouth was performed. Upon anatomopathological examination, the tumor with was classified as a mature teratoma. In the intraoral examination, a deep and atresia palate incomplete cleft palate, bone growth in the region of the posterior alveolar ridge of the maxilla, and in the posterior region of the mandible on the left side, "V" shaped mandible and microglossia, crowding were observed dental agenesis of the lower lateral incisors, absence of caries lesions, gingivitis and enamel development defects. The child will remain under the regular dental pediatric follow-up. Several sequelae were observed in the child's oral cavity and the need for multi-professional follow-up after excision of congenital oropharyngeal teratoma.

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Author Biographies

Letícia Bruno Qualhato, Federal University of Uberlândia

Graduated from the Dentistry Course, Faculty of Dentistry, Federal University of Uberlândia

Uberlândia, Minas Gerais, Brazil.

Ana Carolina Candelas Peixoto, Federal University of Uberlândia

Student of the Dentistry Course, Faculty of Dentistry, Federal University of Uberlândia.

Uberlândia, Minas Gerais, Brazil.

Késia Lara dos Santos Marques, Federal University of Uberlândia

Dental surgeon of the Special Patients Sector at the Dental Hospital of the Federal University of Uberlândia.

Uberlândia, Minas Gerais, Brazil.

Celia Regina Moreira Lanza, Federal University of Uberlândia

Professor in the Department of Clinic, Pathology and Dental Surgery, Faculty of Dentistry, Federal University of Minas Gerais.

Uberlândia, Minas Gerais, Brazil.

Luiz Roberto da Silva, Federal University of Uberlândia

Master in Genetic-Clinical Study in Mental Disability. Pediatric Physician Hospital de Clínicas, Federal University of Uberlândia.

Uberlândia, Minas Gerais, Brazil.

Fabiana Sodré de Oliveira, Federal University of Uberlândia

Professor of Pediatric Dentistry, Faculty of Dentistry, Federal University of Uberlândia.

Uberlândia, Minas Gerais, Brazil.

References

Tonni G, de Felice C, Centini G, Ginanneschi C. Cervical and oral teratoma in the fetus: a systematic review of etiology, pathology, diagnosis, treatment and prognosis. Arch Gynecol Obstet. 2010;282:355-61. doi:10.1007/s00404-010-1500-7. DOI: https://doi.org/10.1007/s00404-010-1500-7

Kundal VK, Gajdhar M, Sharma C, Kundal R. Intraoral teratoma in a newborn presenting as severe respiratory distress. BMJ Case Rep. 2013;(251):1-5. doi:10.1136/bcr-2013-008735. DOI: https://doi.org/10.1136/bcr-2013-008735

Oliveira-Filho AG, Carvalho MH, Bustorff-Silva JM, Sbragia-Neto L, Miyabara S, Oliveira ER. Epignathus: report of a case with successful outcome. J Pediatr Surg. 1988;33:520-521. doi:10.1016/s0022-3468(98)90103-8. DOI: https://doi.org/10.1016/S0022-3468(98)90103-8

Castillo JM, Drut R, Perroni C, Pollono D, Zamar E. Epignatus - Revisión de casos en el Hospital Pediátrico Sor María Ludovica de La Plata. Rev Faso. 2009;(1):1-3.

Peiró JL, Sbragia L, Scorletti F, Lim FY, Shaaban A. Management of fetal teratomas. Pediatr surg int. 2016;32(7):635-647. doi:10.1007/s00383-016-3892-3. DOI: https://doi.org/10.1007/s00383-016-3892-3

Kumar B, Sharma SB. Neonatal oral tumors: congenital epulis and epignathus. J pediatr surg. 2008;43:9-11. doi:10.1016/j.jpedsurg.2008.03.055. DOI: https://doi.org/10.1016/j.jpedsurg.2008.03.055

Kumar SY, Shrikrishna U, Jayaprakash S, Aishwarya S. Epignathus with fetiform features. J of Lab Phys. 2011;3(1):56-58. doi:10.4103/0974-2727.78571. DOI: https://doi.org/10.4103/0974-2727.78571

Chung JH, Farinelli CK, Porto M, Major CA. Fetal Epignathus the case of an early EXIT. Am Coll Obst and Gynecol. 2012;119(2):466-470. DOI: https://doi.org/10.1097/AOG.0b013e318242b3f1

Menezes filho MP, Simão NMMS. Giant epignathus of the palate: a case report. J Bras Patol Med Lab. 2015;51(5):339-343. doi:10.5935/1676-2444.20150055. DOI: https://doi.org/10.5935/1676-2444.20150055

Kumar KM, Veligandla I, Lakshmi ARV, Pandey V. Congenital giant teratoma arising from the hard palate: a rare clinical presentation. J Clin Diagn Res. 2016; 10(7): 3-4. doi:10.7860/JCDR/2016/18863.8083. DOI: https://doi.org/10.7860/JCDR/2016/18863.8083

Jadhav SS, Korday CS, Malik S, Shah VK, Lad SK. Epignathus leading to fatal airway obstruction in a neonate. J Clin Diagn Res. 2017;11(1):SD04–SD05. doi: 10.7860/JCDR/2017/24956.9283. DOI: https://doi.org/10.7860/JCDR/2017/24956.9283

Hamed ME, El Din MHN, Abdelazim IA, Shikanova S, Karimova B, Kanshaiym S. Prenatal diagnosis and immediate successful management of isolated fetal Epignathus. J med ultrasound. 2019;27(4):198-201. doi:10.4103/JMU.JMU_125_18. DOI: https://doi.org/10.4103/JMU.JMU_125_18

Ribeiro MMS, Falone VE, Pacheco TDM, Ferreira SH, Lopes JF, Amaral WND. Epignathus: relato de caso. Rev da soc bras de ultra. 2019;(26):34-36.

Güney D, Bostanci SA, Ertürk A, Öztorun CI, Demir S, Azili MN, et al. Bir Yenidoğanda Epignatus – orofaringeal teratom. Disease. Turk J Pediatr. 2019;1-3. doi:10.12956/tchd.511789. DOI: https://doi.org/10.12956/tchd.511789

Liberato BTG, Rodrigues LM, Carneiro ARS, do Val DR, Didier EFR. Teratoma Oral (epignathus) associado a teratoma cervical gigante congênito: relato de caso e revisão de opções terapêuticas. Rev Med UFC. 2019;59(1):67-70. doi:10.12956/tchd.511789. DOI: https://doi.org/10.20513/2447-6595.2019v59n1p67-70

Sugiyama M, Kanke K, Suenaga H, Isojima T, Fujishiro J, Hoshi K. Neonatal epignathus in the oral and pharyngeal regions: a case report. Oral Sci Int. 2019; 16:40–46. doi:10.1002/osi2.1012. DOI: https://doi.org/10.1002/osi2.1012

Januário LN, Guerra P, dos Santos MN, Tonello C. Teratoma congênito de orofaringe: relato de caso. Int j of Health Manag. 2019;2:1-4. doi:10.1590/S0100-72032005000200008. DOI: https://doi.org/10.1590/S0100-72032005000200008

Aubin A, Pondaven S, Bakhos D, Lardy H, Robier A, Lescanne E. Oropharyngeal teratomas in newborns: management and outcome. Eur ann otorhinolaryngol head neck dis. 2014:1-5. doi:10.1016/j.anorl.2012.05.006. DOI: https://doi.org/10.1016/j.anorl.2012.05.006

Teixeira FAA, Junior FAAT, Aguiar LCB, Barbosa MAC, Sampaio VMR, Freitas RS. Epignatus: relato de dois casos. Rev Bras Cir Craniomaxilofac. 2010;1(13):63-8.

Kontopoulos EV, Gualtieri M, Quintero RA. Successful in utero treatment of an oral teratoma via operative fetoscopy: case report and review of the literature. Am j obstet gynecol. 2012;207(1):12-15. doi:10.1016/j.ajog.2012.04.008. DOI: https://doi.org/10.1016/j.ajog.2012.04.008

Carvalho CHP, Nonaka CFW, Elias CTV, Matheus RCS, Dias RMB, Souza LB, et al. Giant Epignathus teratoma discovered at birth: a case report and 7-year follow-up. Braz dent j. 2017;28(2): 256-261. doi:10.1590/0103-6440201701368. DOI: https://doi.org/10.1590/0103-6440201701368

Ozturk A, Gunay GK, Akin MA, Arslan F, Tekelioglu F, Coban D. Multiple intraoral teratoma in a newborn infant: Epignathus. Fetal pediatr Pathol. 2012;31:210–216. doi:10.3109/15513815.2011.650283. DOI: https://doi.org/10.3109/15513815.2011.650283

Morlino S, Castori M, Servadei F, Laino L, Silvestri E, Grammatico P. Pediatric Craniofacial Malformation (PECRAM) Study Group. Oropharyngeal teratoma, oral duplication, cervical diplomyelia and anencephaly in a 22-week fetus: a review of the craniofacial teratoma syndrome. Birth Defects Res A Clin Mol Teratol. 2015; 103(06):554–566. doi:10.1002/bdra.23327. DOI: https://doi.org/10.1002/bdra.23327

Dohlman G, Sjovall A. Large epignathus-teratoma successfully operated upon immediately after birth. Glasgow Med J. 1953;34(3):123-5.

Sauter ER, Diaz JH, Arensman RM, Butcher III B, Guarisco JL, Hayes DH. The perioperative management of neonates with congenital oropharyngeal teratomas. J Pediatr Surg. 1990;25:925–928. doi:10.1016/j.ciresp.2018.12.001. DOI: https://doi.org/10.1016/0022-3468(90)90231-W

Sales PHH, Rocha SS, Albuquerque AFM, Cunha Filho JF. Tratamento cirúrgico de macrostomia. Re. Cir Traumatol Buco-Maxilo-Fac. 2016;16(4):26-29.

Grabb WC. The first and second branchial arch syndrome. Plast Reconstr Surg. 1965;36(5):485-508. DOI: https://doi.org/10.1097/00006534-196511000-00001

Beluci ML, Genaro KF. Quality of life of individuals with cleft lip and palate pre- and post-surgical correction of dentofacial deformity. Rev Esc Enferm USP. 2016; 50(2):216-221. doi: 10.1590/S0080-623420160000200006. DOI: https://doi.org/10.1590/S0080-623420160000200006

Carreirão S, Pitanguy I. Tratamento da fissura palatina. Conceitos atuais. Cid-Edit. Cient.1989;79(6).325-333.

Voigt S, Park A, Scott A, Vecchiotti MA. Microglossia in a newborn a case report and review of the literature. Arch Otolaryngol Head Neck Surg. 2012;138(8):759-761. doi:10.1001/archoto.2012.1324. DOI: https://doi.org/10.1001/archoto.2012.1324

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Published

01-07-2021

How to Cite

Qualhato, L. B. ., Peixoto, A. C. C. ., Marques, K. L. dos S. ., Lanza, C. R. M. ., Silva, L. R. da ., Mendonça, G. S. de, & Oliveira, F. S. de . (2021). Sequelae of congenital oropharyngeal teratoma in the oral cavity of the child: case report. International Journal for Innovation Education and Research, 9(7), 173–183. https://doi.org/10.31686/ijier.vol9.iss7.3225