Analysis of the frequency of pediatric cancer in the Western Amazon (Brazil) the case of Rondônia

Main Article Content

Carlos Alberto Paraguassu-Chaves
Allan Kardec Duailibe Barros Filho
Carlos de Andrade Macieira
Fabrício Moraes de Almeida
Lenita Rodrigues Moreira Dantas
João Viana Fonseca Neto

Abstract

Objective: Analyzes the frequency of cancer in children and adolescents in the State of Rondônia / Western Amazon (Brazil), attended by public health services. Method: This is a descriptive, quantitative and cross-sectional study. We used an instrument developed by Paraguassú-Chaves et al [24], semi-structured, containing a series of variables, such as sex, age, histological types, types of cancer by location of the primary tumor, lymphomas, leukemias, clinical stage of the disease, diagnosis and previous treatment, among others. We asked the Research Ethics Committee to waive the Free and Informed Consent Term, because the study did not require patient intervention or collection of biological material and there was no possibility of constraints for patients and their families. Results: From 122 cases, 56 (45.9%) were female and 66 (55.1%) were male. Regarding the distribution of patients according to the age group, 38 (31.1%) were younger than 4 years, 21 (17.2%), 5 to 9 years, 24 (19.7%) from 10 to 14 and 39 (32.0%) from 15 to 19. The most frequent histological types by gender were myeloproliferative leukemias and myelodysplastic diseases with 39.31% of new cases, reticuloendothelial lymphomas and neoplasms 11.96%, carcinomas and other epithelial neoplasms 11.96% of cases and CNS and several cranial intra-neoplasms and intraspinal with 11.11% of new cases. Leukemia in the hematopoietic and reticuloendothelial system (C42) is the most frequent cancer in children and adolescents, with 46.2% of cancers in the studied period. 20.5% of the cases do not know the stage of the cancer and 79.5% of the patients do not have information about the stage of the disease. 99.38% of pediatric cancer cases are referred by the single public health system - SUS and only 0.11% non-SUS or private health system. 47.6% of children and adolescents who arrive at the cancer clinic of the public health system have no diagnosis or previous treatment. Conclusions: he results presented are similar to the studies carried out in Rondônia, Brazil and other countries and are in agreement with the studies by Paraguassú-Chaves et al [24], Paraguassú-Chaves et al [27] and Paraguassú-Chaves et al [28].Considering some parameters and indicators, it can be concluded that childhood cancer in Rondônia is a public health problem.

Downloads

Download data is not yet available.

Article Details

How to Cite
Paraguassu-Chaves, C. A. ., Filho, A. K. D. B. ., Macieira, C. de A. ., Almeida, F. M. de ., Dantas, L. R. M. ., & Neto, J. V. F. . (2020). Analysis of the frequency of pediatric cancer in the Western Amazon (Brazil): the case of Rondônia. International Journal for Innovation Education and Research, 8(5), 479-497. https://doi.org/10.31686/ijier.vol8.iss5.2364
Section
Articles
Author Biographies

Carlos Alberto Paraguassu-Chaves, Federal University of Maranhão

Professor

Allan Kardec Duailibe Barros Filho, Federal University of Maranhão

Professor

Carlos de Andrade Macieira, Federal University of Maranhão – HUUFMA

Nephrologist at the University Hospital

Fabrício Moraes de Almeida, Federal University of Rondônia, Brazil

Researcher of the Doctoral and Master Program in Regional Development and Environment (PGDRA/UFRO). Leader of line 2 ― Technological and Systemic Development, and Researcher of GEITEC

Lenita Rodrigues Moreira Dantas, Higher Institute of Health Sciences and Environment of the Amazon – AICSA

Researcher

João Viana Fonseca Neto, Federal University of Maranhão, Brazil

Professor

References

Little J. Epidemioloy of childhood cancer. Lyon: IARC, 1999. (IARC Scientific Publications, 149).

INCA. Instituto Nacional do Câncer. Particularidades do Câncer Infantil [Internet]. Rio de Janeiro: INCA. Disponível em: http://www.inca.gov.br/conteudo_vie w.asp?id=343.

Da Luz JF. Perfil Clínico-Demográfico dos Pacientes Atendidos no Serviço de Oncologia Pediátrica do Hospital de Clínicas de Porto Alegre: Período de jan/2000 a dez/2010 [dissertação]. Porto Alegre (RS): Universidade Federal do Rio Grande do Sul; 2011.

Steliarova-Foucher E, Stiller C, Lacour B, Kaatsch P. International Classification of Childhood Cancer, Third Edition. Bull Am Cancer Soc. 2005 Abr 01; 103(7): 1457-67.

American Cancer Society. About Basal and Squamous Cell Skin Cancer. Atlanta, 2016. Disponivel em: <https://www.cancer.org/content/dam/CRC/PDF/Public/8818.00.pdf >. Acesso em: 21 set. 2019.

American Cancer Society. Cancer facts & figures 2014. Atlanta, 2014. Disponivel em:<https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2014/cancer-facts-and-figures-2014.pdf>. Acesso em:21 set. 2019.

American Cancer Society. Cancer facts & figures 2015. Atlanta, 2015. Disponivel em: <http://oralcancerfoundation.org/wp-content/uploads/2016/03/Us_Cancer_Facts.pdf>. Acesso em: 13 set. 2019.

American Cancer Society. Cancer facts & figures 2017. Atlanta, 2017a. Disponivel em: <https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2017/cancer-facts-and-figures-2017.pdf>. Acesso em:13 set. 2017.

American Cancer Society. Non-Hodgkin Lymphoma Risk Factors. Atlanta, 2017b.Disponivel em: < https://www.cancer.org/content/cancer/en/cancer/non-hodgkinlymphoma/causes-risks-prevention/risk-factors/>. Acesso em: 24 ago. 2019.

Barr R et al. Pediatric Oncology in Countries with limited resources. In: PIZZO, P. A.; POPLACK, D. G. Principles and Pratices of Pediatric Oncology. 5. ed. Philadelphia: Lippincott Willians and Wilkins, 2006. p. 1605-17.

Ferlay J et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in Globocan 2012. International Journal of Cancer, Geneve, v. 136, n. 5, p.359-386, 2015.

Ferlay J et al. Globocan 2012 v1.0, cancer incidence and mortality worldwide. Lyon, France: IARC, 2013. (IARC CancerBase, 11). Disponivel em: <http://globocan.iarc.fr>. Acesso em: 14 set. 2019.

Magrath I, Steliarova-Foucher E, Epelman S, Ribeiro RC, Harif M, Li C-K, Kebudi R, Macfarlan SD, Howard SC. Paediatric cancer in low-income and middle-income countries. The Lancet Oncol, London, v.14, n.3, p 104-116, 2013.

Howlader N. et al. (Ed.). SEER Cancer Statistics Review, 1975-2014. Bethesda: National Cancer Institute, 2017. Disponivel em: <https://seer.cancer.gov/csr/1975_2014/>. Acesso em: 1 ago. 2019.

Parkin DM; Krámarova E; Draper GJ; Masuyer E; Michaelis J; Neglia J; Qureshi S. & Stiller CA. (ed.), 1998.International Incidence of Childhood Cancer. v. 2, IARC Scientific Publications 144. Lyon: International Agency for Research on Cancer/World Health Organization.

Ries LAG, Smith MA, Gurney JG, Linet M, Tamra T, Young JL, Bunin GR (et al). Cancer Incidence and Survival among Children and Adolescents: United States SEER Program 1975-1995. Bethesda: National Cancer Institute, SEER Program; 1999.

INCA - Instituto Nacional de Câncer José Alencar Gomes da Silva. Estimativa 2018-2019: incidência de câncer no Brasil. Rio de Janeiro: INCA; 2017.

Karim-Kos H et al. Trends in incidence, survival and mortality of childhood and adolescente cancer in Austria, 1994-2011. Cancer Epidemiology, Amsterdam, v. 42, p.72-81, 2016.

INCA - Instituto Nacional de Câncer José Alencar Gomes da Silva. Divisão de Comunicação Social – DCS- Relatório de Atividades. Rio de Janeiro. 2013.

INCA - Instituto Nacional de Câncer José Alencar Gomes da Silva. Ministério da Saúde. Estimativa / 2018. Incidência de Câncer no Brasil. Rio de Janeiro. INCA, 2018.

INCA - Instituto Nacional de Câncer José Alencar Gomes da Silva. Ministério da Saúde. Incidência de Câncer no Brasil. Rio de Janeiro. INCA, 2015.

Guerra M.R, Moura GCV, Mendoça GAS. Risco de câncer no Brasil: tendências e estudos epidemiológicos mais recentes. Ver. Bras. cancer. 2005; 51(3):227-34.

Paraguassú-Chaves CA, Silveira EG, Beleza SC, Beleza FC. Perfil epidemiológico de Rondônia. 1ª Ed. Porto Velho, AICSA, 2015b.

Paraguassú-Chaves, CA et al. Analysis of histological frequency and pediatric cancer in Rondônia, Western Amazonia (Brazil). International Journal of Advanced Engineering Research and Science (IJAERS). [Vol-5, Issue-7, July- 2018]. p.60-66.

Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev. 2010 jun; 36(4):277-85.

Li J, Trevor DT, Miller JW, Pollack LA and Stewart SL. Cancer incidence among children and adolescents in the United States, 2001-2003. Pediatrics June. Official Journal of the American Academy of Pediatrics. 2008, 121 (6) e1470-e1477.

Paraguassú-Chaves CA, Silveira EG, Beleza SC, Beleza FC. Perfil epidemiológico do câncer em Rondônia: Amazônia brasileira. 1ª Ed. Porto Velho, AICSA, 2015a.

Paraguassú-Chaves CA, Silveira EG, Beleza SC, Beleza LC (2017). Epidemiologia do câncer em Rondônia. AICSA, Porto Velho.

De Camargo B. et al. Cancer incidence among children and adolescents in Brazil: first report of 14 population based cancer registries. Int. J. Cancer. 2010; 126 (3):715-20.

Silva DB, Pires MMS, Nassar, SM. (2002). Câncer pediátrico: análise de um registro hospitalar. J Pediatr. set/out;78(5):409-14.

Braga PEB, Latorre MRDO, Curado MP. Câncer na infância: análise comparativa da incidência, mortalidade e sobrevida em Goiânia (Brasil) e outros países. Cadernos de Saúde Pública, São Paulo, 2001.

Sharp L, Cotton A, Little J. Descriptive epidemiology. In: Epidemiology of Childhood Cancer (J. Little, ed.), pp.10-66, IARC Scientific Publications 149. Lyon: International Agency for Research on Cancer/World Health Organization. 1999.

Braga, PEB. Câncer na Infância: Tendências e Análise de Sobrevida em Goiânia (1989-1996). Dissertação de Mestrado, São Paulo: Faculdade de Saúde Pública, Universidade de São Paulo, 2000.

Greenberg RS, Shuster JL. 1985. Epidemiology of cancer in children. Epidemiologic Reviews,7:22-48.

Latorre, MRDO, 2000. Epidemiologia dos tumores na infância. In: Pediatria Oncológica (B. Camargo & L. F. Lopes, org.), pp. 7-27, São Paulo: Lemar.

Hada TC, Gaete AEG, Pianovski MAD (2014). Childhood cancer epidemiological profile of patients

referred to the hospital de clínicas of UFP pediatric oncology unit. Câncer pediátrico: perfil epidemiológico dos pacientes atendidos no service de oncologia pediátrica do hospital de clínicas da

UFPR. Rev. Med. UFPR 1(4):141-149 out/dez.

Most read articles by the same author(s)