VITAMIN D, IN THE BEST CLINIC IN AUTOIMMUNE, INFLAMMATORY INFECTIOUS AND DEMELINIZING DISEASES

A CRITICAL ANALYSIS

Authors

  • Eliza Miranda Ramos University of Matogrosso do Sul, Campo Grande, MS, Brazil
  • Dr. Gilberto Gonçalves Facco Universidade Anhanguera - UNIDERP, Campo Grande, MS, Brazil.
  • Dr. Valter Aragão do Nascimento Federal University of Matogrosso do Sul, Campo Grande, MS

DOI:

https://doi.org/10.31686/ijier.vol8.iss4.2130

Keywords:

VITAMIN D

Abstract

The term demyelination is used to characterize any inflammatory changes that occur in the medullary or cephalic region.  Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and in general, besides being inflammatory [08, 25], demyelinating and with significant neuronal degeneration, it is considered an important cause of permanent disability in young adults [02-05]. The inflammatory process occurs by an irregular immune response usually mediated by T cells and acts as autoantigens and leads to destruction of the myelin sheath with genetic predispositions [21]. Thus, these chronic and disabling characteristics place a high cost on public health coffers by temporarily or permanently restricting the economic and social activities of their holders and also impacting the lives of their families in a financial and emotional way [15-18]. Still regarding the high cost treatment to inflammatory-infectious processes, primary and autoimmune demyelinating agents, such as sepsis in the adult and child population is considered a critical disease as the main cause of death in children intensive care in Brazil. In recent years in Brazil [24], the high rate of death from sepsis in Brazilian intensive care units has surpassed deaths from stroke and infarction and approximately 230.000 adult patients undergoing intensive care unit treatment have sepsis and estimated 55.7% of hospitalized patients with sepsis died [24]. It is recognized that Vitamin D deficiency is common in both children and adults hospitalized in severe clinical conditions in intensive care [06-12].

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Author Biographies

Dr. Gilberto Gonçalves Facco, Universidade Anhanguera - UNIDERP, Campo Grande, MS, Brazil.

Departamento de Medicina Veterinária

Dr. Valter Aragão do Nascimento, Federal University of Matogrosso do Sul, Campo Grande, MS

Laboratory of Mineral Metabolism and Biomaterials, Dr. Hélio Mandetta Medical School, 

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Published

01-04-2020

How to Cite

Ramos, E. M. ., Facco, D. G. G. ., & Nascimento, D. V. A. do . (2020). VITAMIN D, IN THE BEST CLINIC IN AUTOIMMUNE, INFLAMMATORY INFECTIOUS AND DEMELINIZING DISEASES: A CRITICAL ANALYSIS. International Journal for Innovation Education and Research, 8(4), 554–559. https://doi.org/10.31686/ijier.vol8.iss4.2130

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